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Muscle Pain, Weakness & Cramps Low calcium levels overstimulate nerves and muscles, leading to muscle cramps, spasms, and twitching  More significant deficiency can cause tetany, a state of sustained, painful muscle contractions often with carpopedal spasms and tingling around the mouth, hands, and feet Muscle Pain, Weakness & Cramps Low calcium levels overstimulate nerves and muscles, leading to muscle cramps, spasms, and twitching  More significant deficiency can cause tetany, a state of sustained, painful muscle contractions often with carpopedal spasms and tingling around the mouth, hands, and feet Prilosec (omeprazole) is a proton pump inhibitor (PPI) that is used to treat the symptoms of ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome  Common side effects of Prilosec include diarrhea, nausea, vomiting, headaches, rash, dizziness, nervousness, abnormal heartbeats, muscle pain, weakness, and infrequently, leg cramps and water retention  Consult your doctor    Can omeprazole cause muscle cramps?People also askSep 15, 2025 · Omeprazole, a proton pump inhibitor, can cause muscle cramps  Learn about the side effects and how to manage them effectively What are the side effects of Prilosec?How do I report negative side effects of Prilosec (omeprazole)?Can I take Prilosec and omeprazole together?Prilosec and Muscle cramps - a phase IV clinical study of FDA data Summary: Muscle cramps is reported as a side effect among people who take Prilosec (omeprazole), especially for people who are female, 60+ old, also take Zocor, and have Osteoporosis  The phase IV clinical study analyzes which people have Muscle cramps when taking Prilosec More on Yahoo ShoppingFeb 5, 2026 · Learn about the side effects of Prilosec (omeprazole), from common to rare, for consumers and healthcare professionals Nov 17, 2025 · This deficiency manifests as muscle cramps, weakness, and, in severe cases, tetany or arrhythmias, directly linking Prilosec use to musculoskeletal discomfort  To mitigate the risk, patients on Prilosec should monitor their magnesium levels through regular blood tests, particularly if symptoms like muscle pain or spasms arise
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