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Access information designed for healthcare professionals, including details about Pfizer medicines and patient support materials Pfizer RxPathways connects eligible patients to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings Spironolactone is a specific pharmacologic antagonist of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule Based on the Randomized Aldactone Evaluation Study (RALES), treatment in conjunction with standard therapy should be initiated at a dose of spironolactone 25 mg once daily in patients with a serum potassium ≤5 0 mEq L and serum creatinine ≤2 5 mg dL Dec 3, 2025 · Aldactone package insert prescribing information for healthcare professionals Includes: indications, dosage, adverse reactions and pharmacology Speak with a Pfizer Medical Information Professional regarding your Pfizer medicine or vaccine inquiry Available 9AM-5PM ET Monday to Friday; excluding holidays Sep 9, 2026 · Aldactone (spironolactone) is a potassium-sparing diuretic that reduces salt absorption while preventing potassium loss It treats heart failure, high blood pressure, low potassium, and fluid retention caused by heart failure, liver cirrhosis, or nephrotic syndrome ALDACTONE® (spironolactone) medication page for healthcare professionals to search for scientific information on Pfizer medications Also find the prescribing information, announcements, resources, and channels to connect with Pfizer Medical
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