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A phase IV clinical study of FDA data: Weight increased is found as a side effect among people who take Tizanidine hydrochloride (tizanidine hydrochloride)Aug 17, 2026 · Learn about the side effects of Zanaflex (tizanidine), from common to rare, for consumers and healthcare professionals Dec 2, 2024 · As with all medications, tizanidine may have side effects Here are several common and serious side effects to watch out for as you’re taking this medication Jan 28, 2017 · I have also been taking tizanidine at night and I have gained approximately 14 lbs in the last two months The tizanidine is the only thing I changed Jun 6, 2026 · Also, adverse long-term side effects of Tizanidine include depression, liver disease, kidney disease, weight gain, and joint pain Dangerous side effects of Tizanidine involve anaphylaxis or allergy, coma, and heart problems Also, it is not recommended in pregnancy or when breastfeeding See full list on ehealthme comAug 16, 2025 · Tizanidine, while causing sleepiness and dizziness, is generally not known to cause weight gain in clinical trials Carisoprodol is also highly sedating, often causing drowsiness Dosage and the duration of use also influence the likelihood and degree of weight-related changes The study uses data from the FDA It is based on tizanidine hydrochloride(the active ingredients of Zanaflex) and Zanaflex (the brand name) Other drugs that have the same active ingredients (e g generic drugs) are not considered Dosage of drugs is not considered in the study