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Sep 17, 2025 · Janumet XR (sitagliptin metformin) is a combination medication for adults with Type 2 diabetes It contains two different diabetes medications that help improve blood sugar control One is sitagliptin, a DPP-4 inhibitor, and the other is metformin, a biguanide Janumet XR is an extended-release tablet that you take once a day To get the most out of the medication, take it along with a See full list on rxlist comyoutube comApr 8, 2025 · Janumet XR side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling) Stop taking Janumet XR and call your doctor right away if you have symptoms of pancreatitis: severe pain in your JANUMET XR tablets combine two antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in adults with type 2 diabetes mellitus: sitagliptin, a dipeptidyl peptidase- 4 (DPP-4) inhibitor, and metformin extended-release, a member of the biguanide class Sitagliptin is a DPP-4 inhibitor, which exerts its actions in youtube comJANUMET XR is a combination of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin hydrochloride (HCl), a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus JANUMET XR can cause serious side effects, including: 1 Lactic Acidosis Metformin, one of the medicines in JANUMET XR, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death Lactic acidosis is a medical emergency and must be treated in the hospital Aug 31, 2026 · Janumet XR package insert prescribing information for healthcare professionals Includes: indications, dosage, adverse reactions and pharmacology youtube comJanumet XR combines a dipeptidyl peptidase-4 (DPP-4) inhibitor (sitagliptin) with a biguanide (metformin) and it is used in adults with type 2 diabetes mellitus